Animal Health, Biosecurity and Antimicrobial Stewardship

INFOGRAPHICS

• Antimicrobial Stewardship and Udder Health on Dairy Farms

• Antimicrobial Use in Calves on Dairy Farms

• Does the Milk Microbiome Play a Role in Increasing Susceptibility to Clinical Mastitis?

• MALDI-TOF: A New Tool for Bacteriological Analysis of Milk

• Are young stock contributing to Johne’s disease in your herd?

• Recommended protocol for the administration of an internal teat sealant for dairy cows

• Protocolo recomendado para la administracion de un sellante interno de pezones en vacas lecheras (spanish version)

TRADE PUBLICATIONS

• Antimicrobial use on Canadian dairy farms

• What’s the cost of Johne’s? It could be more than you think!

• Should we treat clinical mastitis selectively?

• Selective antibiotic use matters

ANIMATED VIDEOS

• Identification of Mastitis-Causing Pathogens: How MALDI-TOF analysis looks deeper

• The Microbiome as an Alternative to Antibiotic Use in Dairy Cows

PODCASTS

• Discussing the Mastitis Network with Trevor DeVries

• One Health Mini Series | Herman Barkema

• One Health Miniseries | Ben Caddey & Ellen de Jong

• One Health Miniseries | Kayley McCubbin & Jennifer Ida

• One Health Miniseries | Waseem Shaukat & Marit Biesheuvel

• One Health Miniseries | Linda Dorrestein

• One Health Miniseries | Larissa Martins & Caroline Pereira

• One Health Miniseries | Anne-Marieke Smid & Berina Traub

WEBINARS

• Surveillance in Action: Canadian Dairy Network of Antimicrobial Stewardship & Resistance

• The Mastitis Network: Science-Based Solutions for the Dairy Industry

• The Latest in Herd Health, Welfare & Productivity

SCIENTIFIC PUBLICATIONS

• Fonseca, M., Heider, L.C., Stryhn, H., McClure, JT., Léger, D., Rizzo, D., Dufour, S., Roy, J.-P., Kelton,5 D.F., Renaud, D.L., Barkema, H.W., Sanchez, J. 2023.  Frequency of isolation and phenotypic antimicrobial resistance of fecal Salmonella enterica recovered from dairy cattle in Canada. J. Dairy Sci. 107(4): 2357-2373.  https://doi.org/10.3168/jds.2023-23937 

• Warder, L.M., Heider, L.C., Léger, D.F., Rizzo, D., McClure, J.T., de Jong, E., McCubbin, K.D., Uyama, T., Fonseca, M., Jaramillo, A.S. and Kelton, D.F. 2023. Quantifying antimicrobial use on Canadian dairy farms using garbage can audits. Frontiers in Veterinary Science, 10. https://doi.org/10.3389/fvets.2023.1185628 

• Fonseca, M., Heider, L.C., Stryhn, H., McClure, J.T., Léger, D., Rizzo, D., Warder, L., Dufour, S., Roy, J.P., Kelton, D.F. and Renaud, D., 2023. Antimicrobial use and its association with the isolation of and antimicrobial resistance in Campylobacter spp. recovered from fecal samples from Canadian dairy herds: A cross-sectional study. Preventive Veterinary Medicine, 215, 105925. https://doi.org/10.1016/j.prevetmed.2023.105925 

• de Jong, E., McCubbin, K.D., Uyama, T., Brummelhuis, C., Bodaneze, J., Kelton, D.F., Dufour, S., Sanchez, J., Roy, J.P., Heider, L.C. and Rizzo, D. 2023. Adoption and decision factors regarding selective treatment of clinical mastitis on Canadian dairy farms. Journal of Dairy Science. https://doi.org/10.3168/jds.2023-23608

• de Jong, E., McCubbin, K.D., Speksnijder, D., Dufour, S., Middleton, J.R., Ruegg, P.L., Lam, T.J., Kelton, D.F., McDougall, S., Godden, S.M. and Lago, A. 2023. Invited review: Selective treatment of clinical mastitis in dairy cattle. Journal of Dairy Science. https://doi.org/10.3168/jds.2022-22826 

• De Jong, E, L. Creytens, S. De Vliegher, K. D. McCubbin, M. Baptiste, A. A. Leung, D. Speksnijder, S. Dufour, J. R. Middleton, P. L. Ruegg, T. J. G. M. Lam, D. F. Kelton, S. McDougall, S. M.
  Godden, A. Lago, P. J. Rajala-Schultz, K. Orsel, V. Krömker, J. P. Kastelic, and H. W. Barkema. 2023. Selective treatment of nonsevere clinical mastitis does not adversely affect cure, somatic cell count, milk yield, recurrence, or culling: A systematic review and meta-analysis. J. Dairy Sci. 106:1267–1286. https://doi.org/10.3168/jds.2022-22271

• McCubbin, K.D., de Jong, E., Brummelhuis, C.M., Bodaneze, J., Biesheuvel, M., Kelton, D.F., Uyama, T., Dufour, S., Sanchez, J., Rizzo, D. and Léger, D., 2023. Antimicrobial and teat sealant use and selection criteria at dry-off on Canadian dairy farms. Journal of Dairy Science, 106(10) 7104-7116. https://doi.org/10.3168/jds.2022-23083 

• McCubbin, K.D., de Jong, E., Lam, T.J., Kelton, D.F., Middleton, J.R., McDougall, S., De Vliegher, S., Godden, S., Rajala-Schultz, P.J., Rowe, S. and Speksnijder, D.C., 2022. Invited review: Selective use of antimicrobials in dairy cattle at drying-off. Journal of Dairy Science. https://doi.org/10.3168/jds.2021-21455 

• Uyama, T., D. F. Kelton, E. I. Morrison, E. de Jong, K. D. McCubbin, H. W. Barkema, S. Dufour, J. Sanchez, L. C. Heider, S. J. LeBlanc, C. B. Winder, J T. McClure, and D. L. Renaud. 2022. Cross-sectional study of antimicrobial use and treatment decision for preweaning Canadian dairy calves. JDS Communications. 3:72-77. https://doi.org/10.3168/jdsc.2021-0161

• Fonseca, M., Heider, L.C., Léger, D., Mcclure, J.T., Rizzo, D., Dufour, S., Kelton, D.F., Renaud, D., Barkema, H.W. and Sanchez J. 2022 Canadian Dairy Network for Antimicrobial Stewardship and Resistance (CaDNetASR): An On-Farm Surveillance System. Front. Vet. Sci. 8:799622. https://doi.org/10.3389/fvets.2021.799622 

• Uyama, T., D. F. Kelton, C. B. Winder, J. Dunn, H. M. Goetz, S. J. LeBlanc, J T. McClure, and D. L. Renaud. Colostrum management practices that improve the transfer of passive immunity in neonatal dairy calves: A scoping review. 2022. PLoS ONE 17(6): e0269824.
  https://doi.org/10.1371/journal.pone.0269824 

• Uyama, T., D. L. Renaud, E. I. Morrison, J T. McClure, S. J. LeBlanc, C. B. Winder, E. de Jong, K.
  D. McCubbin, H. W. Barkema, S. Dufour, J. Sanchez, L. C. Heider and D. F. Kelton. 2022. Associations of calf management practices with antimicrobial use in Canadian dairy calves. J. Dairy Sci. 105:1-14. https://doi.org/10.3168/jds.2022-22299 

• Rowe, S., F. Kabera, S. Dufour, S. Godden, J.-P. Roy, D. Nydam. 2023. Selective dry-cow therapy can be implemented successfully in cows of all milk production levels. J. Dairy Sci. 106(3): 1953-1967. https://doi.org/10.3168/jds.2022-22547 

• Millette G., E. Lacasse, R. Binette, V. Belley, L.P. Chaumont, C. Ster, F. Beaudry, K. Boyapelly, P.L. Boudreault, F. Malouin. 2023. Rationally Designed Pyrimidine Compounds: Promising Novel Antibiotics for the Treatment of Staphylococcus aureus-Associated Bovine Mastitis. Antibiotics (Basel) 12(8): 1344. https://doi.org/10.3390/antibiotics12081344 

• Vanacker N., H.B. Hooper, R. Blouin, P. Lacasse. 2023. Effect of intravenous lipid infusion on biomarkers of insulin resistance and immune functions of dry and nonpregnant dairy cows. J Dairy Sci. 106(3):2113-2123. https://doi.org/10.3168/jds.2022-22309 

• Park, S., D. Jung, I. Altshuler, D. Kurban, S. Dufour, J. Ronholm. 2022. A longitudinal census of the bacterial community in raw milk correlated with Staphylococcus aureus clinical mastitis infections in dairy cattle. Anim. Microbiome 4: 59. https://doi.org/10.1186/s42523-022-00211-x

• Vanacker, N., R. Blouin, C. Ster, P. Lacasse. 2022. Effect of different fatty acids on the proliferation and cytokine production of dairy cow peripheral blood mononuclear cells. J. Dairy Sci. 105 (4): 3508. https://doi.org/10.3168/jds.2021-21296 

• Brouillette, E., C. Goetz, D. Droppa-Almeida, S. Chamberland, M. Jacques, F. Malouin. 2022. Secondary Staphylococcus aureus intramammary colonization is reduced by non-aureus staphylococci exoproducts. Microbes Infect. 24(1): 104879. https://doi.org/10.1016/j.micinf.2021.104879

• Park, S. D. Jung, B. O’Brien, J. Ruffini, F. Dussault, A. Dube-Duquette, É. Demontier, J.-F. Lucier, F. Malouin, S. Dufour, J. Ronholm. 2022. Comparative genomic analysis of Staphylococcus aureus isolates associated with either bovine intramammary infections or human infections demonstrates the importance of restriction-modification systems in host adaptation. 2022. Microb. Genom. 8(2): 000779. https://doi.org/10.1099/mgen.0.000779

• France, A.E., S. Dufour, D.F. Kelton, H.W. Barkema, D. Kurban, T.J. DeVries. 2022. Effect of dry-off management on milking behavior, milk yield, and somatic cell count of dairy cows milked in automated milking systems. J. Dairy Sci. 105 (4): 3544-3558. https://doi.org/10.3168/jds.2021-21383 

• Kurban, D., J.-P. Roy, F. Kabera, A. Fréchette, M.M. Um, A. Albaaj, S. Rowe, S. Godden, P.R.F. Adkins, J.R. Middleton, M.-L. Gauthier, G.P. Keefe, T.J. DeVries, D.F. Kelton, P. Moroni, M. Veiga Dos Santos, H.W. Barkema, S. Dufour. 2022. Diagnosing Intramammary Infection: Meta-Analysis and Mapping Review on Frequency and Udder Health Relevance of Microorganism Species Isolated from Bovine Milk Samples. Animals (Basel). 12(23): 3288. 
  https://doi.org/10.3390/ani12233288 

• Park, S., J. Ronholm. 2021. Staphylococcus aureus in Agriculture: Lessons in Evolution from a Multispecies Pathogen. Clin. Microbiol. Rev. 34(2): e00182-20. 
  http://doi.org/10.1128/CMR.00182-20   

• Jung, D., S. Park, J. Ruffini, S. Dufour, J. Ronholm. 2021. Draft Genome Sequences of 113 Escherichia coli strains Isolated from Intramammary Infections in Dairy Cattle. Microbiol. Resour. Announc. 10(7). 
  http://doi.org/10.1128/MRA.01464-20

• Jung, D., S. Park, J. Ruffini, F. Dussault, S. Dufour, J. Ronholm. 2021. Comparative genomic analysis of Escherichia coli isolates from cases of bovine clinical mastitis identifies nine specific pathotype marker genes. Microb. Genom. 7(7): 000597. https://doi.org/10.1099/mgen.0.000597

• Demontier, E., A. Dubé-Duquette, E. Brouillette, A. Larose, C. Ster, J. F. Lucier, S. Rodrigue, S. Park, D. Jung, J. Ruffini, J. Ronholm, S. Dufour, J.P. Roy, S. Ramanathan, F. Malouin. 2021. Relative virulence of Staphylococcus aureus bovine mastitis strains representing the main Canadian spa types and clonal complexes as determined using in vitro and in vivo mastitis models. J. Dairy Sci. 104(11): 11904-11921. https://doi.org/10.3168/jds.2020-19904 

• Ster C, M. Allard, J. Côté-Gravel, S. Boulanger, P. Lacasse, F. Malouin. 2021. Immune and experimental infection responses of dairy cows vaccinated with the combination of six Staphylococcus aureus proteins that are expressed during bovine intramammary infection and a triple adjuvant. Vet. Immunol. Immunopathol. 238: 110290. https://doi.org/10.1016/j.vetimm.2021.110290. 

• S. Park, D. Jung, S. Dufour, J. Ronholm. 2020. Draft Genome Sequences of 27 Staphylococcus aureus strains and 3 Staphylococcus Species strains Isolated from Bovine Intramammary infection. Microbiol. Resour. Announc. 9(19). https://doi.org/10.1128/MRA.00300-20  

• Cavalcante, P.A., C.G. Knight, Y.L. Tan, A.P.A. Monteiro, H.W. Barkema, E.R. Cobo. 2020. Cathelicidins Mitigate Staphylococcus aureus Mastitis and Reduce Bacterial Invasion in Murine Mammary Epithelium. Infect Immun. 88(7): e00230- 20. http://doi.org/10.1128/IAI.00230-20 

• Cheng J., J. Zhang, B. Han, H.W. Barkema , E.R. Cobo, J.P. Kastelic, M. Zhou, Y. Shi, J. Wang, R. Yang, J. Gao. 2020. Klebsiella pneumoniae isolated from bovine mastitis is cytopathogenic for bovine mammary epithelial cells. J Dairy Sci. 103(4): 3493-3504. https://doi.org/10.3168/jds.2019-17458 

• Dufour, S., J. Labrie, M.Jacques. 2019. The Mastitis Pathogens Culture Collection. ASM Journals. Microbiol. Resour. Announc. 8(15).   https://doi.org/10.1128/mra.00133-19 

• Dr. Barkema’s Google Scholar profile (in the area of infectious disease): https://scholar.google.com/citations?hl=en&user=VaLlkyoAAAAJ&view_op=list_works&sortby=pubdate